Macrophage Mediation in Normal and Diabetic Wound Healing Responses

March 7, 2020
Springer Link

The failure in timely healing of wounds is a central feature in chronic wounds that leads to physiological, psychological and economic burdens. Macrophages have been demonstrated to have various functions in wounds including host defense, the promotion and resolution of inflammation, the removal of apoptotic cells and tissue restoration following injury.

Read More

Review of Dermal Regenerative Template Demonstrates Success in Treatment of Avascular Wounds

February 28, 2020
Vascular News

A combined literature review and retrospective study has confirmed that the use of a dermal regenerative template is “a viable option for providing vascularised coverage over wounds with avascular components”. Moreover, it was also found by Ronald N Bogdasarian (Rutgers New Jersey Medical School, Newark, USA) and colleagues that DRT is less successful in chronic wounds.

Read More

A Rare Case of Neisseria Animaloris Hand Infection and Associated Non-healing Wound

February 27, 2020

Neisseria animaloris is a rare pathogen in humans primarily associated with dog and cat bites. Fourteen cases have been documented in the literature related to the difficulty in identifying this bacterium in the laboratory. We present a patient case demonstrating a prolonged treatment course, which is often seen as the result of misdiagnosis, and subsequent nonhealing wound requiring multiple surgeries and eventual wide excision with staged graft coverage.

Read More

A newly published multicentre RCT demonstrates Smith+Nephew PICO single use NPWT as superior to traditional NPWT in reducing wound area, depth and volume in DFUs and VLUs

January 16, 2020
Business Wire

Smith+Nephew, the global medical technology business, is excited to announce the publication of results from a new randomised controlled trial demonstrating that the use of PICO◊ Single Use Negative Pressure Wound Therapy System significantly reduced wound area, depth and volume compared with traditional negative pressure wound therapy in patients with venous leg ulcers and diabetic foot ulcers.

Read More

Beta-caryophyllene enhances wound healing through multiple routes

December 16, 2019
Plos One

Beta-caryophyllene is an odoriferous bicyclic sesquiterpene found in various herbs and spices. Recently, it was found that beta-caryophyllene is a ligand of the cannabinoid receptor 2 (CB2). Activation of CB2 will decrease pain, a major signal for inflammatory responses.

Read More